Glycoprotein IIb/IIIa Inhibitors for Heart Attack and Unstable Angina
|Generic Name||Brand Name|
|abciximab||ReoPro, Integrilin, Aggrastat|
|eptifibatide||ReoPro, Integrilin, Aggrastat|
|tirofiban||ReoPro, Integrilin, Aggrastat|
How It Works
These medicines prevent the formation of blood clots. They can help prevent blood clots in the coronary arteries after a heart attack.
Why It Is Used
Glycoprotein IIb/IIIa inhibitors might be used with angioplasty after a heart attack. But they are not used for everyone.
How Well It Works
Glycoprotein IIb/IIIa inhibitors may help certain people who have angioplasty after a heart attack, such as people who are at high risk for serious blood clots.1
Glycoprotein IIb/IIIa inhibitors are given in the hospital. So a person is watched closely for any side effects.
Bleeding inside the body is the most common side effect.
See Drug Reference for a full list of side effects. (Drug Reference is not available in all systems.)
What To Think About
Glycoprotein IIb/IIIa inhibitors are only used in the hospital.
Complete the new medication information form (PDF)(What is a PDF document?) to help you understand this medication.
Kushner KG, et al. (2009). 2009 focused updates: ACC/AHA guidelines for the management of patients with ST-elevated myocardial infarction (Updating the 2004 guideline and 2007 focused update) and ACC/AHA/SCAI guidelines on percutaneous coronary intervention (Updating the 2005 guideline and 2007 focused update). A report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Circulation, 120(22): 2271–2306.
|Primary Medical Reviewer||Kathleen Romito, MD - Family Medicine|
|Primary Medical Reviewer||E. Gregory Thompson, MD - Internal Medicine|
|Specialist Medical Reviewer||Stephen Fort, MD, MRCP, FRCPC - Interventional Cardiology|
|Last Revised||April 29, 2011|