Selective Serotonin Reuptake Inhibitors (SSRIs) for Depression in Children and Teens
How It Works
Selective serotonin reuptake inhibitors (SSRIs) can restore the balance of certain brain chemicals (neurotransmitters) that regulate mood. When these brain chemicals are in proper balance, the symptoms of depression may be relieved.
Why It Is Used
Selective serotonin reuptake inhibitors are used to treat depression and anxiety.
How Well It Works
All medicines have side effects. But many people don't feel the side effects, or they are able to deal with them. Ask your pharmacist about the side effects of each medicine your child takes. Side effects are also listed in the information that comes with the medicine.
Here are some important things to think about:
Call your doctor if your child has:
Common side effects of this medicine include:
See Drug Reference for a full list of side effects. (Drug Reference is not available in all systems.)
The U.S. Food and Drug Administration (FDA) has issued an advisory on antidepressant medicines and the risk of suicide. Talk to your doctor about these possible side effects and the warning signs of suicide.
Taking triptans, used for headaches, with SSRIs (selective serotonin reuptake inhibitors) or SNRIs (selective serotonin/norepinephrine reuptake inhibitors) can cause a very rare but serious condition called serotonin syndrome.
What To Think About
Although fluoxetine and escitalopram are often the first selective serotonin reuptake inhibitors (SSRI) used for the treatment of symptoms of depression in children and teens, doctors also prescribe others. People respond to medicines differently.
For some children or teens, another SSRI for treatment of symptoms of depression may be more effective than fluoxetine or escitalopram. If another SSRI is not effective, sometimes doctors may use another type of antidepressant to treat depression in children and teens.
Your child may start to feel better within 1 to 3 weeks of taking an SSRI. But it can take as many as 6 to 8 weeks to see more improvement. If you have questions or concerns about the medicine, or if you do not notice any improvement by 3 weeks, talk to your child's doctor.
Do not suddenly stop taking antidepressants. The use of antidepressants should be tapered off slowly and only under the supervision of a doctor. Abruptly stopping antidepressant medicines can cause negative side effects or a relapse into another depression episode.
Medicine is one of the many tools your doctor has to treat a health problem. If your child takes medicine as your doctor suggests, it will improve your child's health and may prevent future problems. If your child doesn't take the medicines properly, his or her health may be at risk.
There are many reasons why people have trouble taking their medicines. But in most cases, there is something you can do. For suggestions on how to work around common problems, see the topic Taking Medicines as Prescribed.
Advice for women
If your teen is pregnant or breast-feeding, do not use any medicines unless her doctor tells you to. Some medicines can harm the baby. This includes prescription and over-the-counter medicines, vitamins, herbs, and supplements. And make sure that all of your teen's doctors know that she is pregnant or breast-feeding.
Follow-up care is a key part of your child's treatment and safety. Be sure to make and go to all appointments, and call your doctor if your child is having problems. It's also a good idea to know your child's test results and keep a list of the medicines your child takes.
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