Anticonvulsants for Chronic Pain
How It Works
Why It Is Used
Anticonvulsant drugs typically are used to control seizures in people who have epilepsy. These drugs may also be used to treat other painful conditions, such as postherpetic neuralgia and fibromyalgia.
How Well It Works
Some anticonvulsant drugs may work better than others for certain conditions. Anticonvulsants seem to work best when they are used for nerve pain. Examples of nerve pain include postherpetic neuralgia and diabetic peripheral neuropathy.
About 7 out of 10 people with nerve pain who take carbamazepine have some relief from their pain, at least for a short time.1
Gabapentin helps about 3 to 4 out of 10 people who take it for nerve pain.2
Do not suddenly stop taking an anticonvulsant. Your doctor will slowly reduce the dose of this medicine so that you won't have withdrawal symptoms such as anxiety, nausea, pain, sweating, and insomnia.
The U.S. Food and Drug Administration (FDA) has issued a warning on anticonvulsants and the risk of suicide and suicidal thoughts. The FDA does not recommend that people stop using these medicines. Instead, people who take anticonvulsant medicine should be watched closely for warning signs of suicide. People who take anticonvulsant medicine and who are worried about this side effect should talk with a doctor.
See Drug Reference for a full list of side effects. (Drug Reference is not available in all systems.)
What To Think About
Medicine will be started in low doses and then slowly increased until it effectively reduces your chronic pain.
Anticonvulsants are not safe for everyone. To avoid side effects and complications, be sure to tell your doctor about all medical conditions you have and other medicines you are taking.
Anticonvulsants may increase the chance of birth defects. If you are pregnant or thinking of getting pregnant, talk to your doctor before taking medicines. Women who use topiramate during pregnancy have a slightly higher chance of having a baby with birth defects. If you are pregnant or planning to get pregnant, you and your doctor must weigh the risks of using this medicine against the risks of not treating your condition.
eMedicineHealth Medical Reference from Healthwise
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