Monoamine Oxidase Inhibitors (MAOIs) for Panic Disorder
How It Works
Why It Is Used
Monoamine oxidase inhibitors (MAOIs) are usually given to people who have panic disorder and who:
How Well It Works
Although MAOIs are as effective as other antidepressants for treating panic disorder, other antidepressant medicines such as selective serotonin reuptake inhibitors (SSRIs) or tricyclic antidepressants are typically tried first because they have less serious side effects.
All medicines have side effects. But many people don't feel the side effects, or they are able to deal with them. Ask your pharmacist about the side effects of each medicine you take. Side effects are also listed in the information that comes with your medicine.
Here are some important things to think about:
Call your doctor right away if you have:
Common side effects of this medicine include:
Serious reactions—or even death—can result when MAOIs are combined with some foods and medicines. While taking MAOIs, you must avoid eating certain foods, including many alcoholic and caffeinated drinks, sour cream and yogurt, bananas, chocolate, and some cheeses such as American, cheddar, and Swiss. Eating these foods can cause severe high blood pressure and other health problems. Talk with your doctor about diet and medicine restrictions that you need to follow if you are planning to take an MAOI.
You must wait at least 14 days after you stop taking MAOIs before taking another antidepressant. Common nonprescription medicines, particularly certain cold remedies and diet pills, can also be dangerous when taken with an MAOI.
MAOIs can cause death if they are taken in overdose.
The U.S. Food and Drug Administration (FDA) has issued an advisory on antidepressant medicines and the risk of suicide. Talk to your doctor about these possible side effects and the warning signs of suicide.
See Drug Reference for a full list of side effects. (Drug Reference is not available in all systems.)
What To Think About
Medicine is one of the many tools your doctor has to treat a health problem. Taking medicine as your doctor suggests will improve your health and may prevent future problems. If you don't take your medicines properly, you may be putting your health (and perhaps your life) at risk.
There are many reasons why people have trouble taking their medicine. But in most cases, there is something you can do. For suggestions on how to work around common problems, see the topic Taking Medicines as Prescribed.
Advice for women
Taking medicines for panic disorder during pregnancy may increase the risk of birth defects. If you are pregnant, breast-feeding, or trying to get pregnant, talk to your doctor. Medicines may need to be continued if your panic disorder is severe. Your doctor can help weigh the risks of treatment against the risk of harm to your pregnancy.
Follow-up care is a key part of your treatment and safety. Be sure to make and go to all appointments, and call your doctor if you are having problems. It's also a good idea to know your test results and keep a list of the medicines you take.
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