Definition of Genome, Vibrio cholerae

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Genome, Vibrio cholerae: The genome of the bacterium that causes cholera. This genome contains over 4 million bases in its DNA including the sequences for nearly 4,000 genes.

The Vibrio cholerae genome is remarkable in that it is arranged in two circular chromosomes. The larger of the two chromosomes has the usual housekeeping genes, similar to those, for example, of E. coli, the common colon bacillus. The smaller chromosome contains many of the genetic elements that make Vibrio cholerae pathogenic (capable of causing disease).