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Definition of Genoplasty

Genoplasty: A technology that uses the repair mechanisms normally present in cells to repair gene defects.

In genoplasty, a short oligonucleotide fragment is introduced into the cell to simulate a normal DNA sequence and this deceives the cell into repairing itself. The sequence of the gene itself is thus changed permanently.

Genoplasty is different from gene therapy in which a normal gene is inserted into the cell.

Source: MedTerms™ Medical Dictionary
http://www.medterms.com/script/main/art.asp?articlekey=15500
Last Editorial Review: 6/14/2012

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