Definition of MelorheostosisMelorheostosis: A rare bone condition that usually begins in childhood and is characterized by thickening of the bones (sclerosis) of a limb. Pain is frequent in the involved limb, and the affected bone can have the appearance of dripping candle wax on an X-ray. Source: MedTerms™ Medical Dictionaryhttp://www.medterms.com/script/main/art.asp?articlekey=15639 Last Editorial Review: 3/19/2012
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