Definition of Restless leg syndromeRestless leg syndrome: An uncomfortable (creeping, crawling, tingling, pulling, twitching, tearing, aching, throbbing, prickling, or grabbing) sensation in the calves that occurs while sitting or while lying down. The result is an uncontrollable urge to relieve the uncomfortable sensation by http://www.medterms.com/script/main/art.asp?articlekey=16440 Last Editorial Review: 3/19/2012
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