Definition of SigmoidSigmoid: In human anatomy, the lower colon (the lower portion of the large bowel). Sigmoid is short for sigmoid colon. From the Greek letter sigma, which is shaped like a C. Sigmoid also means curved in two directions like the letter S. For example, a sigmoid curve is an S-shaped curve. Source: MedTerms™ Medical Dictionaryhttp://www.medterms.com/script/main/art.asp?articlekey=17535 Last Editorial Review: 3/19/2012
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