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Definition of Darier disease

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Darier disease: A genetic skin disease characterized by slowly progressive hardening of the skin (keratoses) around the hair follicles. This disorder is inherited in an autosomal dominant manner and is due to mutation in a gene called ATP2A2 on chromosome 12. Also known as keratosis follicularis.

Source: MedTerms™ Medical Dictionary
http://www.medterms.com/script/main/art.asp?articlekey=19449
Last Editorial Review: 4/27/2011 5:27:15 PM