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Definition of Antisense mRNA

Antisense mRNA: An mRNA (messenger RNA) transcript that is complementary to endogenous mRNA. Antisense mRNA is the noncoding strand complementary to the coding sequence of mRNA. Introducing a transgene coding for antisense mRNA is a strategy used to block expression of a gene of interest.

Source: MedTerms™ Medical Dictionary
Last Editorial Review: 6/14/2012

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