Definition of Immunoglobulin MImmunoglobulin M: A class of immunoglobulins found in blood and lymph fluid that are the first type of antibody made in response to an infection. Abbreviated IgM. IgM antibodies make up about 5 percent to 10 percent of all the antibodies in the body. Source: MedTerms™ Medical Dictionaryhttp://www.medterms.com/script/main/art.asp?articlekey=21068 Last Editorial Review: 3/19/2012
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