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Definition of ACE (angiotensin converting enzyme)

ACE (angiotensin converting enzyme): The angiotensins are peptides (substances smaller than proteins) that act as vasoconstricting agents (causing blood vessels to narrow). Narrowing the diameter of the blood vessels sends up the blood pressure.

ACE converts angiotensin to its activated form (called angiotensin II) enabling it to function.

The ACE inhibitors are drugs that inhibit the formation of angiotensin II and are used for blood pressure control and congestive heart failure. The ACE inhibitors include benazepril (brand name: Lotensin), captopril (brand name: Capoten), lisinopril (brand names: Zestril and Prinivil), quinapril (brand name: Accupril), and ramipril (brand name: Altace).

Source: MedTerms™ Medical Dictionary
http://www.medterms.com/script/main/art.asp?articlekey=2107
Last Editorial Review: 1/20/1999


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