Definition of Oligonucleotide probeOligonucleotide probe: A short sequence of nucleotides that are synthesized to match a specific region of DNA or RNA then used as a molecular probe to detect the specific DNA or RNA sequence. Source: MedTerms™ Medical Dictionaryhttp://www.medterms.com/script/main/art.asp?articlekey=21290 Last Editorial Review: 3/19/2012
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