Definition of Ankle-foot orthosisAnkle-foot orthosis: A brace, usually made of plastic, that is worn on the lower leg and foot to support the ankle, hold the foot and ankle in the correct position and correct foot drop. Abbreviated AFO. Also known as foot drop brace. Source: MedTerms™ Medical Dictionaryhttp://www.medterms.com/script/main/art.asp?articlekey=2262 Last Editorial Review: 3/19/2012
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