Definition of Liver spotLiver spot: A pigmented flat spot on sun-exposed skin in older adults, especially on the back of the hands and on the forehead. Liver spots are benign. Medically called a senile lentigo. Source: MedTerms™ Medical Dictionaryhttp://www.medterms.com/script/main/art.asp?articlekey=24467 Last Editorial Review: 6/14/2012
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