Definition of OsteoblastOsteoblast: A cell that makes bone. It does so by producing a matrix that then becomes mineralized. Bone mass is maintained by a balance between the activity of osteoblasts that form bone and other cells called osteoclasts that break it down. Source: MedTerms™ Medical Dictionaryhttp://www.medterms.com/script/main/art.asp?articlekey=24502 Last Editorial Review: 3/19/2012
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