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Definition of Exemestane

Exemestane: An oral antiestrogen. Exemestane inhibits the enzyme aromatase in the adrenal glands that produces the estrogens (estradiol and estrone) and thereby lowers their levels. It works by decreasing the amount of estrogen the body makes. This can slow or stop the growth of many types of breast cancer cells that need estrogen to grow. Brand name: Aromasin.

See also: Aromatase inhibitor.

Source: MedTerms™ Medical Dictionary
http://www.medicinenet.com/script/main/art.asp?articlekey=24618
Last Editorial Review: 9/20/2012

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