Definition of FillerFiller: An inactive substance used to make the active medicine easier to measure. For example, fillers are often used in tablets or capsules because the amount of active drug is too small to be handled conveniently. Source: MedTerms™ Medical Dictionaryhttp://www.medterms.com/script/main/art.asp?articlekey=24767 Last Editorial Review: 9/20/2012
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