Definition of ToothacheToothache: Pain in the tooth or gum. The most common cause of a toothache is a cavity or an injury to a tooth that exposes the pulp, which is heavily supplied by nerves. Source: MedTerms™ Medical Dictionaryhttp://www.medterms.com/script/main/art.asp?articlekey=25128 Last Editorial Review: 3/19/2012
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