Definition of Transcription factorTranscription factor: A protein that controls when genes are switched on or off -- whether genes are transcribed or not. Transcription factors bind to regulatory regions in the genome and help control gene expression. Source: MedTerms™ Medical Dictionaryhttp://www.medterms.com/script/main/art.asp?articlekey=25194 Last Editorial Review: 6/14/2012
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