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Definition of Scaffold

Scaffold: 1. In genetics, the chromosome structure consisting entirely of nonhistone proteins remaining after all the DNA and histone proteins have been removed from a chromosome.
2. In genomic mapping, a series of contigs that are in the right order but not necessarily connected in one continuous stretch of sequence.

Source: MedTerms™ Medical Dictionary
http://www.medterms.com/script/main/art.asp?articlekey=25223
Last Editorial Review: 6/14/2012

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