Definition of Burn, second degreeBurn, second degree: A burn severe enough to cause blistering of the skin. The pain of a second-degree burn is usually somewhat more intense than the pain of a first-degree burn. Source: MedTerms™ Medical Dictionaryhttp://www.medterms.com/script/main/art.asp?articlekey=2556 Last Editorial Review: 3/19/2012
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