Definition of CentromereCentromere: The 'waist' of the chromosome that is essential for the division and retention of the chromosome in the cell. The centromere is a uniquely specialized region of the chromosome to which spindle fibers attach during cell division. Source: MedTerms™ Medical Dictionaryhttp://www.medterms.com/script/main/art.asp?articlekey=2668 Last Editorial Review: 3/19/2012
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