Definition of Designer estrogen

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Designer estrogen: An engineered drug that possesses some, but not all, of the actions of estrogen. Also known as selective estrogen-receptor modulator (SERM). For example, raloxifene (brand name: Evista) is classified as a designer estrogen because, like estrogen, it prevents bone loss and lowers serum cholesterol; however, it does not stimulate the endometrial lining of the uterus.