Definition of Cyclooxygenase-1Cyclooxygenase-1: Cyclooxygenase-1, an enzyme that acts to speed up the production of certain chemical messengers, called prostaglandins, in a variety of areas of the body such as the stomach, kidneys, and sites of inflammation. In the stomach, prostaglandins promote the production of a protective natural mucus lining. They also interact within certain cells that are responsible for inflammation and other functions. Source: MedTerms™ Medical Dictionaryhttp://www.medterms.com/script/main/art.asp?articlekey=31217 Last Editorial Review: 3/30/2012
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