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Definition of Cyclooxygenase-2

Cyclooxygenase-2: Cyclooxygenase-2, an enzyme that acts to speed up the production of certain chemical messengers, called prostaglandins that play a key role in in promoting inflammation. When cox-2 activity is blocked, inflammation is reduced. Unlike cox-1, cox-2 is active only at the site of inflammation, not in the stomach.

Source: MedTerms™ Medical Dictionary
Last Editorial Review: 3/30/2012

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