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Definition of Glutathione S-transferase

Glutathione S-transferase: A family of enzymes that utilize glutathione in reactions contributing to the transformation of a wide range of compounds, including carcinogens, therapeutic drugs, and products of oxidative stress.

The glutathione S-transferases act by catalyzing the reaction of glutathione with an acceptor molecule to form an S-substituted glutathione (S = sulfur). See also: Glutathione S-transferase omega-1.

Source: MedTerms™ Medical Dictionary
http://www.medicinenet.com/script/main/art.asp?articlekey=31473
Last Editorial Review: 9/25/2012

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