Definition of Dystonia, Segawa

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Dystonia, Segawa: An important variant form of dopa-responsive dystonia (DRD).

DRD typically begins in childhood or adolescence with progressive difficulty in walking and, in some cases, with spasticity. DRD, by definition, can be successfully treated with dopa.

In Segawa dystonia, the symptoms fluctuate during the day from relative mobility in the morning to increasingly worse disability in the afternoon and evening and after exercise.