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Definition of Cell fusion

Cell fusion: The melding of two or more cells into one cell called a heterokaryon. A heterokaryon may reproduce itself for at least several generations. Cell fusion provides a method for assigning specific genes to specific chromosomes.

When an undifferentiated stem cell fuses with a mature differentiated cell, the resultant cell can retain the mature cell phenotype.

Source: MedTerms™ Medical Dictionary
Last Editorial Review: 6/14/2012

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