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Definition of E2F3

E2F3: E2F transcription factor 3.

E2F3 is a gene on chromosome 6p22 that is a member of the E2F family of transcription factors.

E2F3 may be a key gene in modulating the aggressivity of prostate cancer. E2F3 is present in a high proportion (67%) of prostate cancers. Men with prostate cancer exhibiting detectable E2F3 expression have poorer survival than those without detectable E2F3 expression.

Source: MedTerms™ Medical Dictionary
http://www.medicinenet.com/script/main/art.asp?articlekey=33164
Last Editorial Review: 6/14/2012

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