Definition of Glioblastoma multiformeGlioblastoma multiforme: A highly malignant, rapidly growing type of brain tumor that arises from glial cells in the brain. Early symptoms may include sleepiness, headache, and vomiting. Also called a grade IV astrocytoma. Treatment can involve surgery and radiation treatment. Source: MedTerms™ Medical Dictionaryhttp://www.medterms.com/script/main/art.asp?articlekey=3603 Last Editorial Review: 3/19/2012
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