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Definition of Hybridoma

Hybridoma: A hybrid cell used as the basis for the production of antibodies in large amounts for diagnostic or therapeutic use. Hybridomas are produced by injecting a specific antigen into a mouse, collecting an antibody-producing cell from the mouse's spleen, and fusing it with a tumor cell called a myeloma cell. The hybridoma cells multiply indefinitely in the laboratory and can be used to produce a specific antibody indefinitely.

Source: MedTerms™ Medical Dictionary
http://www.medicinenet.com/script/main/art.asp?articlekey=3823
Last Editorial Review: 3/19/2012

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