Definition of HeterotrisomyHeterotrisomy: Trisomy of different chromosomes. The occurrence of two children in the same family, one with trisomy 18 and the other with trisomy 21, is an instance of heterotrisomy. See also: Homotrisomy. Source: MedTerms™ Medical Dictionaryhttp://www.medterms.com/script/main/art.asp?articlekey=38320 Last Editorial Review: 10/9/2012
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