Definition of Pyrophosphate arthropathyPyrophosphate arthropathy: Joint damage due to deposition of calcium pyrophosphate. Pyrophosphate arthropathy most commonly affects the knees, wrists and knuckles and tends to be symmetrical. Source: MedTerms™ Medical Dictionaryhttp://www.medterms.com/script/main/art.asp?articlekey=38394 Last Editorial Review: 6/14/2012
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