Medical Definition of MADH4
MADH4: A tumor suppressor gene (also known as SMAD4/DPC4) located on chromosome 18 in band 18q21 1. About 15% to 20% of cases of juvenile polyposis are due to germline mutations in MADH4. About 90% of pancreatic carcinomas show homozgous loss (loss of both copies) of MADH4.Source: MedTerms™ Medical Dictionary
Last Editorial Review: 9/14/2016
Medical Dictionary Definitions A - Z
Search Medical Dictionary
- What Is Inherited Lipodystrophy?
- Do You Take Good Care of Your Eyes?
- Tips for a Clean Home & Healthy Cat