Definition of Discordant coupleDiscordant couple: A pair of long-term sexual partners in which one has a sexually transmitted infection and the other does not. The CDC has guidelines for counseling discordant couples in which the woman is HIV-infected and her husband is HIV-uninfected. Source: MedTerms™ Medical Dictionaryhttp://www.medterms.com/script/main/art.asp?articlekey=38933 Last Editorial Review: 6/14/2012
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