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Definition of In situ hybridization

In situ hybridization: The use of a DNA or RNA probe to detect complementary genetic material in cells or tissue. In situ hybridization involves hybridizing a labeled nucleic acid to suitably prepared cells or tissues on microscope slides to allow visualization in situ (in the normal location).

Source: MedTerms™ Medical Dictionary
http://www.medterms.com/script/main/art.asp?articlekey=3988
Last Editorial Review: 3/19/2012

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