Definition of Interventricular septumInterventricular septum: The stout wall that separates the lower chambers (the ventricles) of the heart from one another. A hole in the interventricular septum is termed a ventricular septal defect (VSD). Source: MedTerms™ Medical Dictionaryhttp://www.medterms.com/script/main/art.asp?articlekey=4002 Last Editorial Review: 3/19/2012
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