Definition of PeriappendicealPeriappendiceal: Near the appendix. Perforation of the appendix can lead to a periappendiceal abscess (a collection of pus near the appendix). Source: MedTerms™ Medical Dictionaryhttp://www.medterms.com/script/main/art.asp?articlekey=40107 Last Editorial Review: 6/14/2012
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