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Definition of Mega- (prefix)

Mega- (prefix): The combining form "mega-" comes from the Greek "megas", great or big and means abnormally large. Examples include: Megalocephaly is too large a head. Megacardia is too large a heart. Megacolon is too large a colon.

Source: MedTerms™ Medical Dictionary
http://www.medicinenet.com/script/main/art.asp?articlekey=4331
Last Editorial Review: 9/20/2012

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