Definition of Pleural spacePleural space: The tiny area between the two layers of the pleura (the thin covering that protects and cushions the lungs). The pleural space is normally filled with a small amount of fluid. Source: MedTerms™ Medical Dictionaryhttp://www.medterms.com/script/main/art.asp?articlekey=4947 Last Editorial Review: 4/27/2011 5:27:15 PM
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