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Definition of Proband

Proband: The family member through whom a family's medical history comes to attention. For example, a proband might be a baby with Down syndrome. The proband may also be called the index case, propositus (if male), or proposita (if female).

Source: MedTerms™ Medical Dictionary
http://www.medterms.com/script/main/art.asp?articlekey=5051
Last Editorial Review: 3/19/2012

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