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Definition of Propositus

Propositus: The initial subject presenting a mental or physical disorder, who causes a study of his or her heredity in order to determine if other members of the family have had the same disease or carry it. Also called index case and proband.

Source: MedTerms™ Medical Dictionary
http://www.medterms.com/script/main/art.asp?articlekey=5069
Last Editorial Review: 10/30/2013

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