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Definition of Sign

Sign: Any objective evidence of disease, as opposed to a symptom, which is, by nature, subjective. For example, gross blood in the stool is a sign of disease; it is evidence that can be recognized by the patient, physician, nurse, or someone else. Abdominal pain is a symptom; it is something only the patient can perceive.

Source: MedTerms™ Medical Dictionary
Last Editorial Review: 3/19/2012

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