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Definition of VEGF

VEGF: Vascular endothelial growth factor, a substance made by cells that stimulates the formation of new blood vessels, a process called angiogenesis. VEGF also acts as a mitogen for vascular endothelial (vessel lining) cells, stimulating these cells to divide and multiply.

VEGF is a polypeptide. It is structurally related to platelet-derived growth factor (PDGF). The gene for VEGF is on chromosome 6p12.

Source: MedTerms™ Medical Dictionary
http://www.medterms.com/script/main/art.asp?articlekey=5969
Last Editorial Review: 6/14/2012

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