Definition of Specific-pathogen freeSpecific-pathogen free: A term that is applied to animals reared for use in laboratory experiments which indicates that the animals are known to be free of germs that can cause disease. Abbreviated SPF. Source: MedTerms™ Medical Dictionaryhttp://www.medterms.com/script/main/art.asp?articlekey=6331 Last Editorial Review: 3/19/2012
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