Definition of Loeys-Dietz syndrome

Loeys-Dietz syndrome: An inherited syndrome characterized by aortic aneurysms and other blood vessel abnormalities in children. The condition is often associated with other birth defects. The aortic aneurysms of Loeys-Dietz syndrome are prone to rupture at a smaller size than other aneurysms, with early identification of the condition and surgical intervention critical for survival.