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Definition of Brittle bone disease

Brittle bone disease: Osteogenesis imperfecta, not one but a group of genetic diseases, all of which affect collagen, a key component of connective tissue in tissues like bone, tendon and skin. All types of osteogenesis imperfecta result in fragile bones.

Source: MedTerms™ Medical Dictionary
Last Editorial Review: 8/28/2013

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