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Definition of Chromosome, dicentric

Chromosome, dicentric: A chromosome that is abnormal in that it has two centromeres rather than one. Because the centromere is essential for chromosome division, a dicentric chromosome is pulled in opposite directions when the cell divides. This causes the chromosome to form a bridge and then break and be unstable.

Source: MedTerms™ Medical Dictionary
http://www.medicinenet.com/script/main/art.asp?articlekey=6764
Last Editorial Review: 3/19/2012

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